Patrick Manser
Postdoctoral Researcher in Technology-enhanced Training for Brain Health
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Patrick Manser
Postdoctoral Researcher in Technology-enhanced Training for Brain Health
Department of Neurobiology, Care Sciences and Society
Karolinska Institute
Welcome note:
My mission as a researcher:
My research focuses on the iterative co-design, purpose-development, and evaluation of innovative and individually tailored technology-enhanced training concepts for neurodegenerative and neurological disorders. My mission is to rigorously commit to patient-centered and multidisciplinary research by advancing research methodologies and putting them into practice to collaboratively create credible, well-accepted, and effective solutions that have the potential to enhance clinical practice and improve care for individuals in need.
To make the most out of this process, I put a strong emphasis on the involvement of primary (individuals with neurodegenerative or neurological disorders) and secondary (i.e., healthcare professionals as well as relatives and carers) end-users, other researchers, as well as experts from the (exergaming) industry. I am particularly interested in combining the advantages of qualitative and quantitative research and in combining a wide range of assessment techniques, including domain-specific neuropsychological assessments, various clinical protocols of (instrumented) physical activity, gait and mobility analysis (with accelerometry), and neuroimaging (i.e., electroencephalography, and (functional) magnetic resonance imaging).
My medium-term goals are to investigate dose-response relationships between training components and their effectiveness, to further improve the personalization of technology-enhanced training approaches, and to investigate their mechanism of action across different etiologies or subtypes of neurodegenerative and neurological disorders.
The roots of my passion for research:
My passion for research began during my time as a competitive track and field athlete. I was particularly drawn to technically complex disciplines such as javelin throwing and pole vaulting, where I sought to optimize my training routines to perfect my technique and maximize performance.
To further develop my knowledge and use it to make a tangible impact in the real world, this journey led me to become a professional fitness trainer, allowing me to use my expertise to help others achieve their goals and improve their health. Over three years, I developed a particular fascination with the broader effects of physical activity and exercise beyond the neuromuscular system. This realization inspired me to pursue a career as an academic researcher with the goal of one day advancing knowledge about the role of physical activity and exercise in health promotion and disease prevention.
To this end, I started studying Health Sciences and Technology at ETH Zurich in 2016 and started contributing to research early on as a research assistant. During my Master’s degree, I had the opportunity to contribute to a project that developed and evaluated an exergame-based motor-cognitive training for chronic stroke patients. As soon as I started this project, I felt that I’d found my professional passion and had finally “arrived” where I always belonged, as this work aimed to integrate the knowledge of several fields that have captivated me, including exercise science, neuroscience, neuropsychology, behaviour change, and emerging technologies. This experience solidified my desire to one day make a tangible contribution to the advancement of the field - and thus to the prevention and treatment of patients with neurodegenerative and neurological diseases.
Fortunately, I was given the opportunity to continue on this path by completing my Dr. Sc. ETH between August 2020 and April 2024 in the laboratory of Prof. Dr. Eling D. de Bruin. I coordinated the iterative co-design, development, and evaluation of the ‘Brain-IT’ training concept for the secondary prevention of mild neurocognitive disorder. This process resulted in a new intervention type specifically targeting various relevant mechanisms of action to alleviate the pathological state of mild neurocognitive disorder by combining an individually tailored exergame-based motor-cognitive training with biofeedback-guided resonance breathing. This project was my first significant contribution to the field and has definitely reinforced my calling as an academic researcher.
My private life:
Outside of life as a researcher, I am still a sports enthusiast (although no longer competitively) and enjoy taking bastu (that's how the Swedes call Saunas here), watching documentaries, and spending time with friends and family, including my two cats, Daisy and Stella. These activities help me maintain a balanced and fulfilling lifestyle.