Patrick Manser

Postdoctoral Researcher in Technology-enhanced Training for Brain Health at Karolinska Institute

Science thrives on collaboration and critical discussion. If you're curious to learn more about my work, open to engaging with my mission, or interested in building a shared vision, I’d love to hear from you. Please get in touch via email (see above) or through one of the platforms below.

Beyond FITT-How Density Can Improve the Understanding of the Dose-Response Relationship Between Physical Activity and Brain Health

Journal article

Fabian Herold, Liye Zou, Paula Theobald, Patrick Manser, Ryan S Falck, Qian Yu, Teresa Liu-Ambrose, Charles H Hillman, Arthur K Kramer, Kirk I Erickson, Boris Cheval, Yanxia Chen, Matthew Heath, Zhihao Zhang, Toru Ishihara, Keita Kamijo, Soichi Ando, Yanping Gao, Joseph T. Costello, Meijun Hou, Mats Hallgren, Zhihui Chen, David Moreau, Vahid Farrahi, David A. Raichlen, Emmanuel Stamatakis, Michael J. Wheeler, Neville Owen, Sebastian Ludyga, Henning Budde, Thomas Gronwald
SportRxiv, Society for Transparency, Openness, and Replication in Kinesology, 2024

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APA Click to copy
Herold, F., Zou, L., Theobald, P., Manser, P., Falck, R. S., Yu, Q., … Gronwald, T. (2024). Beyond FITT-How Density Can Improve the Understanding of the Dose-Response Relationship Between Physical Activity and Brain Health. SportRxiv.

Chicago/Turabian Click to copy
Herold, Fabian, Liye Zou, Paula Theobald, Patrick Manser, Ryan S Falck, Qian Yu, Teresa Liu-Ambrose, et al. “Beyond FITT-How Density Can Improve the Understanding of the Dose-Response Relationship Between Physical Activity and Brain Health.” SportRxiv (2024).

MLA Click to copy
Herold, Fabian, et al. “Beyond FITT-How Density Can Improve the Understanding of the Dose-Response Relationship Between Physical Activity and Brain Health.” SportRxiv, Society for Transparency, Openness, and Replication in Kinesology, 2024.

BibTeX Click to copy

@article{herold2024a,
  title = {Beyond FITT-How Density Can Improve the Understanding of the Dose-Response Relationship Between Physical Activity and Brain Health},
  year = {2024},
  journal = {SportRxiv},
  publisher = {Society for Transparency, Openness, and Replication in Kinesology},
  author = {Herold, Fabian and Zou, Liye and Theobald, Paula and Manser, Patrick and Falck, Ryan S and Yu, Qian and Liu-Ambrose, Teresa and Hillman, Charles H and Kramer, Arthur K and Erickson, Kirk I and Cheval, Boris and Chen, Yanxia and Heath, Matthew and Zhang, Zhihao and Ishihara, Toru and Kamijo, Keita and Ando, Soichi and Gao, Yanping and Costello, Joseph T. and Hou, Meijun and Hallgren, Mats and Chen, Zhihui and Moreau, David and Farrahi, Vahid and Raichlen, David A. and Stamatakis, Emmanuel and Wheeler, Michael J. and Owen, Neville and Ludyga, Sebastian and Budde, Henning and Gronwald, Thomas}
}

Abstract:

Research on physical activity and health, including planned and structured forms such as acute and chronic physical exercise, has focused on understanding potential dose-response relationships. Traditionally, the variables of (i) Frequency, (ii) Intensity, (iii) Time, (iv) and Type (known as the FITT principle) have been used to operationalize the dose of physical activity. In this article, we describe the limitations of FITT and propose that it should be complemented by the underappreciated variable density, which defines the temporal distribution of physical activity stimuli within a single bout of physical activity or between successive bouts of physical activity relative to time spent resting (e.g., in napping/sleeping or sedentary behaviors). Using the field of physical activity and brain health as an example, we discuss challenges and opportunities for further research to use density to improve our understanding of dose-response relationships between physical activity and health-related outcomes.