ParkMOVE (05.2024 - now)
Moving towards personalized rehabilitation for Parkinson’s disease informed by diversity, exercise responders and brain activity during motion
The ParkMOVE project is a large multidisciplinary project led by Prof. Dr. Erika Franzén at the Karolinska Institutet with the ultimate aim to reduce the disease burden and, particularly, the risk of falls as well as increase health-related quality of life by individually tailored training protocols in individuals with Parkinson's disease.
The focus of the project is to develop a precision rehabilitation approach that is (i) personalized based on multimodal data (i.e., motor, clinical, neuropsychological and neuroimaging) to inform decision making on the type, content, and characteristics of the training and (ii) individually tailored and progressed according to real-time physiological and exercise performance data. To do so, the project is structured in 4 phases:
Stages 1 to 3 focused on building the groundwork for improving individualized tailoring of training on the basis of the exploration of motor-cognitive performance between young adults, older adults, and individuals with PD (stage 1), classification of PD subtypes (stage 2), and characterization of predictors for (non-)responders to the HiBalance training in PD (stage 3).
My responsibility is to coordinate Stage 4 of the projects which builds on the findings of these three previous stages and aims to iteratively co-design, purpose-develop, test, refine, and evaluate a novel hybrid exergame-based motor-cognitive training concept for the secondary/tertiary prevention of PD.
The focus of the project is to develop a precision rehabilitation approach that is (i) personalized based on multimodal data (i.e., motor, clinical, neuropsychological and neuroimaging) to inform decision making on the type, content, and characteristics of the training and (ii) individually tailored and progressed according to real-time physiological and exercise performance data. To do so, the project is structured in 4 phases:
Stages 1 to 3 focused on building the groundwork for improving individualized tailoring of training on the basis of the exploration of motor-cognitive performance between young adults, older adults, and individuals with PD (stage 1), classification of PD subtypes (stage 2), and characterization of predictors for (non-)responders to the HiBalance training in PD (stage 3).
My responsibility is to coordinate Stage 4 of the projects which builds on the findings of these three previous stages and aims to iteratively co-design, purpose-develop, test, refine, and evaluate a novel hybrid exergame-based motor-cognitive training concept for the secondary/tertiary prevention of PD.
Based on our experience and key learnings from previous projects, we are currently working with leading researchers in the field to develop a consensus-based refined methodological guideline for the iterative Co-design, purpose-Development, and evaluation of Individually tailored Technology-enhanced Training concepts (Co-Develop-IT) including a checklist to facilitate the effective implementation and reporting of these guidelines (see project Co-Develop-IT).
Stage 4 of the ParkMOVE project implements these guidelines. We provide a step-by-step application example in the manuscript presenting the Co-Develop-IT guideline which has recently been published here: Co-Develop-IT - Co-design, Development, and Evaluation of Individually Tailored Technology-Enhanced Training and Rehabilitation Concepts: Methodological Guideline Development Study.
We are currently working oh Phase 2 of implementing the Co-Develop-IT guideline. The aim of this phase of the project is to elaborate a comprehensive set of design and implementation requirements for our solutions to be developed. To ensure we consider all relevant viewpoints of interest holders together with existing scientific evidence, we are working on a narrative synthesis of the literature together with two qualitative studies – one study with individuals with PD (primary end-users) and one focus group study with the remaining interest holders.
Stage 4 of the ParkMOVE project implements these guidelines. We provide a step-by-step application example in the manuscript presenting the Co-Develop-IT guideline which has recently been published here: Co-Develop-IT - Co-design, Development, and Evaluation of Individually Tailored Technology-Enhanced Training and Rehabilitation Concepts: Methodological Guideline Development Study.
We are currently working oh Phase 2 of implementing the Co-Develop-IT guideline. The aim of this phase of the project is to elaborate a comprehensive set of design and implementation requirements for our solutions to be developed. To ensure we consider all relevant viewpoints of interest holders together with existing scientific evidence, we are working on a narrative synthesis of the literature together with two qualitative studies – one study with individuals with PD (primary end-users) and one focus group study with the remaining interest holders.