Patrick Manser

Postdoctoral Researcher in Technology-enhanced Training for Brain Health at Karolinska Institute


Curriculum vitae



Science thrives on collaboration and critical discussion. If you're curious to learn more about my work, open to engaging with my mission, or interested in building a shared vision, I’d love to hear from you. Please get in touch via email (see above) or through one of the platforms below.



Beyond FITT: Addressing Density in Understanding the Dose-Response Relationships of Physical Activity with Health - An Example Based on Brain Health [in press]


Journal article


Fabian Herold, Liye Zou, Paula Theobald, Patrick Manser, Ryan S Falck, Qian Yu, Teresa Liu-Ambrose, Charles H Hillman, Arthur K Kramer, Kirk I Erickson, Boris Cheval, Yanxia Chen, Matthew Heath, Zhihao Zhang, Toru Ishihara, Keita Kamijo, Soichi Ando, Yanping Gao, Joseph T. Costello, Meijun Hou, Mats Hallgren, Zhihui Chen, David Moreau, Vahid Farrahi, David A. Raichlen, Emmanuel Stamatakis, Michael J. Wheeler, Neville Owen, Sebastian Ludyga, Henning Budde, Thomas Gronwald
European Journal of Applied Physiology

Cite

Cite

APA   Click to copy
Herold, F., Zou, L., Theobald, P., Manser, P., Falck, R. S., Yu, Q., … Gronwald, T. Beyond FITT: Addressing Density in Understanding the Dose-Response Relationships of Physical Activity with Health - An Example Based on Brain Health [in press]. European Journal of Applied Physiology.


Chicago/Turabian   Click to copy
Herold, Fabian, Liye Zou, Paula Theobald, Patrick Manser, Ryan S Falck, Qian Yu, Teresa Liu-Ambrose, et al. “Beyond FITT: Addressing Density in Understanding the Dose-Response Relationships of Physical Activity with Health - An Example Based on Brain Health [in Press].” European Journal of Applied Physiology (n.d.).


MLA   Click to copy
Herold, Fabian, et al. “Beyond FITT: Addressing Density in Understanding the Dose-Response Relationships of Physical Activity with Health - An Example Based on Brain Health [in Press].” European Journal of Applied Physiology.


BibTeX   Click to copy

@article{herold-a,
  title = {Beyond FITT: Addressing Density in Understanding the Dose-Response Relationships of Physical Activity with Health - An Example Based on Brain Health [in press]},
  journal = {European Journal of Applied Physiology},
  author = {Herold, Fabian and Zou, Liye and Theobald, Paula and Manser, Patrick and Falck, Ryan S and Yu, Qian and Liu-Ambrose, Teresa and Hillman, Charles H and Kramer, Arthur K and Erickson, Kirk I and Cheval, Boris and Chen, Yanxia and Heath, Matthew and Zhang, Zhihao and Ishihara, Toru and Kamijo, Keita and Ando, Soichi and Gao, Yanping and Costello, Joseph T. and Hou, Meijun and Hallgren, Mats and Chen, Zhihui and Moreau, David and Farrahi, Vahid and Raichlen, David A. and Stamatakis, Emmanuel and Wheeler, Michael J. and Owen, Neville and Ludyga, Sebastian and Budde, Henning and Gronwald, Thomas}
}

Abstract:

Research on physical activity (PA) and health has a fundamental concern with dose-response relationships. The variables of (1) Frequency, (2) Intensity, (3) Time, and (4) Type (i.e., the FITT principle) have traditionally been used to operationalize the dosage of PA. We consider some limitations of FITT and propose that it can be complemented by the additional variable density (from the German exercise and training variable Belastungsdichte), which can be defined as the timing of successive work bouts within a single PA bout as well as the timing between successive PA bouts within a specific time period; it does so by quantifying the temporal intervals between successive work or PA bouts (i.e., time spent at a lower PA intensity or resting such as in napping/sleeping or sedentary behaviors). Using the field of PA and brain health as an example, we discuss the opportunities and challenges for further research employing the variable density and consider its potential to improve the understanding of dose-response relationships between PA and health outcomes. 


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